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Course Outline
Introduction to NGS and Forensic Applications
- Overview of DNA sequencing technologies.
- Advantages of NGS over traditional forensic methods.
- Common forensic applications of NGS.
Fundamentals of Forensic Genetics
- DNA markers used in forensic analysis.
- Short Tandem Repeats (STRs) and Single Nucleotide Polymorphisms (SNPs).
- Mitochondrial DNA and Y-chromosome analysis.
NGS Workflows in Forensic Casework
- Sample preparation and library construction.
- Sequencing protocols for forensic samples.
- Quality control and contamination prevention.
Bioinformatics and NGS Data Analysis
- NGS data processing and alignment.
- Variant calling and forensic interpretation.
- Software tools for forensic genomic analysis.
Forensic Anthropology and Ancestry Determination
- Genetic markers for ancestry and population studies.
- NGS applications in ancient and degraded DNA analysis.
- Case studies in forensic anthropology.
NGS for Challenging and Degraded Samples
- Techniques for low-quality and low-quantity DNA.
- Dealing with environmental and mixed DNA samples.
- NGS applications in missing persons and disaster victim identification.
Legal, Ethical, and Regulatory Considerations
- Privacy concerns in forensic genomics.
- Regulatory frameworks for forensic DNA databases.
- Ethical challenges in forensic genetic analysis.
Future Trends in Forensic Genomics
- Advancements in sequencing technology.
- Integration of AI in forensic genetics.
- Emerging forensic applications of NGS.
Summary and Next Steps
Requirements
- Basic knowledge of genetics and forensic science.
- Familiarity with DNA sequencing concepts.
Audience
- Forensic scientists and geneticists.
- Anthropologists and bioarchaeologists.
- Law enforcement officers and forensic investigators.
14 Hours
